Multiple mutations within individual oncogenes
نویسندگان
چکیده
منابع مشابه
Mutations of the ras Proto - Oncogenes in Childhood
ras gene mutations are the most frequent molecular changes found in the preleukemic syndromes of adults and may play a role in initiating these diseases and in their progression to acute leukemia. However, little is known about the incidence or importance of these genetic mutations in childhood myeloproliferative states (MPS). The bone marrow (BM) monosomy 7 syndrome accounts for a large percen...
متن کاملMutations of the ras proto-oncogenes in childhood monosomy 7.
ras gene mutations are the most frequent molecular changes found in the preleukemic syndromes of adults and may play a role in initiating these diseases and in their progression to acute leukemia. However, little is known about the incidence or importance of these genetic mutations in childhood myeloproliferative states (MPS). The bone marrow (BM) monosomy 7 syndrome accounts for a large percen...
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Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 tumors were examined using PCR-based fluorescent DNA technology. Amplification of the three oncogenes and the mutation of K-ras were correlated wi...
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The merger of vowels in a language over time has been a productive area of study, yet how these changes arise remains an ongoing matter of debate. A generally accepted hypothesis is that mergers arise within individuals, who are thought to become merged over time as a result of contact with other merged individuals. A further prediction states that unconditioned mergers, such as the low back me...
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ژورنال
عنوان ژورنال: Cancer Science
سال: 2021
ISSN: 1347-9032,1349-7006
DOI: 10.1111/cas.14699